C8981
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C8981
Sigma-Aldrich
Carbamazepine
meets USP testing specifications
| Synonym: | 5H-Dibenz[b,f]azepine-5-carboxamide |
| CAS Number: | 298-46-4 |
| Linear Formula: | C15H12N2O |
| Molecular Weight: | 236.27 |
| EC Number: | 206-062-7 |
| MDL number: | MFCD00005073 |
| PubChem Substance ID: | 24893120 |
Description
| Biochem/physiol Actions | Anticonvulsant; ligand for the GABAA receptor benzodiazepine modulatory site. |
| Sodium channel inhibitor |
Properties
| mp | 191-192 °C(lit.) |
| suitability | meets USP testing specifications |
| Gene Information | human ... PRNP(5621), SCN5A(6331) |
| rat ... Scn2a1(24766), Scnn1a(25122), Scnn1g(24768), Slc6a1(79212) | |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22-42/43 |
| Safety Statements | 22-36/37/39 |
| WGK Germany | 2 |
| RTECS | HN8225000 |
References
| reference | Ichikawa, J., Valproate and carbamazepine increase prefrontal dopamine release by 5-HT1A receptor activation. Eur. J. Pharmacol. 380, R1-3, (1999) |
| Afanas'ev, I., Lamotrigine and carbamazepine affect differently the release of D-3Haspartate from mouse cerebral cortex slices: involvement of NO. Neurochem. Res. 24, 1153, (1999) | |
| Merck | Merck 13,1788 |
| Corp MSDS 1, 680:A / FT-IR 2 (2), 3066:D / FT-NMR 1 (2), 1451:A / RegBook 1 (2), 2073:E / Sax 6, 902 / Structure Index 1, 328:C:5 |
